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BIOBASE Databases at NIH

To use these tools, you will require your NIH domain username (not prefixed by 'nih\') and NIH domain password. This is a secure server, and all communications are encrypted.

TransPath
Signal Transduction Pathways
ExPlain_2.0New
ExPlain_2.3
In Version 2.0New, CMA bug was fixed which was found in Version 2.0
In version 2.3, all analysis and functions work fine.
However, since BKL license is in process,
links to BKL will not work for now.
If linking to entries is important for user's analysis, please use version 2.0New instead.
Gene Expression Analysis
TransFac
Transcription Factor Database

TransPro
Human, Mouse and Rat Gene
Promoter Sequence Database

TransCompel
Composite Gene Regulatory
Element Database Module
TrxFac Miner
Human genome transcription factors

Tools available on this server:
The ExPlain Analysis System promotes biological interpretation of high throughput experiments like microarrays, proteomic data, and ChIP-chip experiments. The intuitive workflow allows systematic creation of experimentally testable hypothesis for both gene transcription regulation and signalling networks. [More info]

TransPath provides data about molecules participating in signal transduction pathways and the reactions they are involved in, resulting in a complex network of interconnected signalling components. PathwayBuilder can retrieve and visualize any part of the overall network starting with any molecule or reaction. ArrayAnalyzer is a tool for identification of common key regulators in the signaling network which can serve as drug targets. [More info]
TransFac is a database on eukaryotic cis-acting regulatory DNA elements and trans-acting factors. It covers the whole range from yeast to human. [More info]
TransPro is a substantial collection of human, mouse and rat promoter sequences. [More info]
TransCompel comprises specialized data on composite regulatory elements. [More info]
TrxFac Miner is a web-based interface that uses the Transfac database to report all known genes in the human genome that are near or overlap a chosen transcription activation factor binding site. (developed by David Hoover, CIT, NIH)

The databases and tools on this server are available to all NIH personnel. TransFac, TransPath and ExPlain were developed by BIOBASE International. This server is maintained by the Helix Systems, CIT, NIH.


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Maintained by the Helix Systems, CIT, NIH.
Contact: staff@helix.nih.gov.